Purpose This study was designed to examine the effects of 8 weeks of circuit exercise training on blood lipids, insulin resistance, cardiovascular function, and metabolic syndrome risk factors in 40~50s male bus drivers. Methods Twenty-nine bus drivers were randomly assigned to one of two groups, i.e., circuit exercise training group (TR: n=14) and control group (CON: n=15). Subjects in TR participated in circuit exercise training 30-40 min per session, three sessions per week for 8 weeks, whereas subjects in CON were asked to maintain their normal life pattern for same intervention period. The variables regarding body composition, blood lipids, insulin resistance, cardiovascular function, and number of metabolic syndrome risk factors were measured and compared between two groups as well as between pre- and post-test. Data were analyzed using repeated two-way ANOVA with post hoc test. Results Main results of the present study were as follows: 1) Waist circumference, waist-hip ratio, body mass index, and percent body fat decreased significantly in TR. 2) LDL-C decreased and HDL-C increased significantly in TR. 3) Fasting plasma insulin and HOMA-IR decreased significantly in TR. 4) Regarding cardiovascular function, diastolic blood pressure and mean arterial pressure decreased significantly in both TR and CON. hs-CRP were not changed significantly; however, it tended to be decreased TR. 5) Number of metabolic syndrome risk factors decreased significantly in TR(2.86±0.86 to 1.50±0.76). Conclusions It was concluded that 8 weeks of circuit exercise training would be beneficial for improvement of blood lipid profiles and insulin resistance, resulting in preventing metabolic syndrome. In particular, it would be very clinically meaningful that number of metabolic syndrome risk factors decreased from 2.86±0.86 to 1.50±0.76 by the circuit exercise training.
Purpose The purpose of this study was to investigate the effect of a 10-week aerobic exercise training on cardiovascular function, atherosclerosis, and vascular endothelial function in elderly women. Methods Twenty impaired fasting glucose (IFG) and normoglycemic elderly women volunteered to participate in the study. The participants in aerobic exercise training group (TR: n=9) completed 20-40 minutes of aerobic exercise program at 30-50% HRR for 3 times per week during 10 weeks. The participants in control group (CON: n=11) were asked to maintain their normal life pattern during the same intervention period. Results Main results of the study were as follows: 1) There were no significant main effect or interaction in body weight, fat-free mass, fat mass, percent body fat, and body mass index. 2) There were no significant main effect or interaction in heart rate, stroke volume, cardiac output, total peripheral resistance (TPR), systolic blood pressure, diastolic blood pressure, mean arterial blood pressure, pulse pressure, and rate pressure product. However, interaction between group and test in TPR was close to statistically significant level (P =.054), and it tended to be decreased in TR group. 3) There was a significant main effect of test in high sensitivity C-reactive protein(hs-CRP), it tended to be decreased in TR group. There were no significant changes in total cholesterol(TC)/high density lipoprotein-cholesterol (HDL-C) ratio, triglyceride/HDL-C ratio, and low density lipoprotein-cholesterol/HDL-C ratio. 4) There were significant main effect of group, main effect of test, as well as interaction between group and test in % flow mediated dilation(FMD), and it increased significantly (P<.01) in TR group. Nitric oxide tended to be increased in TR group, even though it did not change significantly in both groups. Conclusions It was concluded that the 10-week aerobic exercise training would be beneficial for improvement of vascular endothelial function, resulting from the decrement of total peripheral resistance.
Purpose The study was designed to compare physical fitness, indices of lifestyle disease, and biochemical property of muscle according to sarcopenia and obesity in elderly women. Methods One hundred elderly women were alloted to one of four groups, i.e., sarcopenia+obesity (SO: n=20) group, sarcopenia (S: n=20) group, obesity (O: n=29) group, and normal (N: n=31) group. Criterion for sarcopenia was 'appendicular skeletal muscle mass (ASM)/height2<5.4 kg/㎡', and criterion for obesity was 'percent body fat>35%'. Dependent variables regarding physical fitness, lifestyle disease, and biochemical property of muscle were measured and compared among four groups. Results 1) Regarding daily living fitness, grip strength, upper arm flexion, sit-and-reach, up and go, and VO2max in SO group and S group were significantly lower than N group. Regarding isokinetic function, peak torque and average power in SO group and S group were significantly lower, and relative values to body weight in SO group and O group were significantly lower than N group. 2) Regarding hypertension, resting HR and RPP in SO group and O group were significantly higher than S group and N group. Regarding diabetes mellitus, fasting plasma glucose and HOMA-IR in SO group and O group were significantly higher than S group and N group. Regarding hyperlipidemia, HDL-C in SO group and O group were significantly lower than S group and N group. Regarding atherosclerosis, TC/HDL-C ratio and LDL-C/HDL-C ratio in SO group and O group were significantly higher than S group and N group. 3) Regarding biochemical property of muscle, IL-6 in SO group and O group were significantly higher than S group and N group. Conclusion It was concluded that physical fitness was declined in sarcopenia elderly, and that relative value of isokinetic function, indices of lifestyle disease, and inflammation markers were deteriorated in obesity elderly. Especially, the decline and deterioration of physical fitness and indices of lifestyle disease were even more severe in the elderly who had the both status. Therefore, the efforts should be made to prevent and improve sarcopenia and/or obesity.
