Purpose The purpose of this study was to examine the effects of 16 weeks’ combined exercise training on insulin resistance, inflammatory markers, oxidative stress, leukocyte telomere length, body composition, and daily living fitness in elderly women with type 2 diabetes mellitus (DM). Methods Twenty-eight participants were randomly assigned into one of two groups, i.e., exercise training group (EX: n=14) and control group (CON: n=14). Subjects in EX participated in 3 sessions of 60 min-combined exercise for 16 weeks, whereas subjects in CON were asked to maintain their normal life pattern during the same period. The variables regarding insulin resistance, inflammatory markers, oxidative stress, leukocyte telomere length, body composition, and daily living fitness were measured and compared between two groups as well as between pre-post test utilizing a repeated two-way ANOVA. Results Main results were as follows: 1) Fasting plasma insulin and HOMA-IR tended to decrease in EX, whereas increased significantly in CON. 2) IL-6, TNF-α, hs-CRP decreased in EX, but the changes were not statistically significant. 3) MDA increased significantly and GPx decreased significantly in both EX and CON. 4) Leukocyte telomere length increased significantly in EX. 5) Fat-free mass increased in EX, whereas fat mass and percent body fat decreased significantly in EX. 6) Arm curl, chair stand, sit & reach, tandem test, 10m walking speed, and up & go improved significantly in EX. Conclusion It was concluded that the combined exercise for 16 weeks had a positive effect on improving insulin resistance, increasing leukocyte telomere length, as well as enhancing body composition and daily living fitness in elderly women with type 2 diabetes.
The purpose of this study was to investigate the effects of 8 weeks of aerobic training and resveratrol supplementation on a body composition, physical fitness, insulin resistance, liver function, blood pressure, and heart rate. Fifty-one elderly women were randomly assigned to aerobic training group (EX: n=12), resveratrol supplementation group (R: n=13), combined aerobic training and resveratrol supplementation group (EX+R: n=12), and control group (CON: n=14). The subjects in EX group exercised three sessions per week, 40 minutes per session for 8 weeks, the subjects in R group took 500 mg of resveratrol per day for 8 weeks, and the subjects in EX+R group received both treatments. The subjects in CON group were asked to maintain normal daily life pattern without any treatment for the same period of intervention. Body composition, physical fitness, insulin resistance, liver function, blood pressure, and heart rate were measured at pre- and post-test and the data were compared among groups and between tests by utilizing two-way ANOVA with repeated measures. Main results of the present study were as follows: 1) Physique and body composition did not change significantly in all groups. 2) Muscular endurance increased significantly in EX+R group, whereas the other physical fitness-related variables showed no significant changes in all groups. 3) Fasting glucose, fasting insulin, HOMA-IR, and HbA1c tended to be improved in EX+R group. 4) AST, ALT, and γ·GT showed no significant changes in all groups. 5) Systolic blood pressure and diastolic blood pressure increased significantly in CON group. Heart rate tended to be decreased in EX+R group and EX group. It was concluded that the 8 weeks of aerobic training and resveratrol supplementation had positive effects on muscular endurance, insulin resistance, and blood pressure in T2DM elderly women. Research investigating the effects of a longer period of aerobic training and resveratrol supplementation on the same variables would be warranted in the future.
The objective of this study was to investigate the effects of 12-weeks of vitamin D supplementation and circuit training on skeletal muscle mass in elderly women with type 2 diabetes mellitus and vitamin D deficiency. Forty eight elderly women with type-2 diabetes mellitus and vitamin D deficiency were randomly assigned to control(n=10), vitamin D supplement(n=11), exercise(n=12), and vitamin D supplement+exercise(n=15) groups. Dependent variables were measured before and after the 12-week interventions. Major outcomes included body composition, fasting glucose, insulin, and 25(OH)D concentration. ASM(apeendicular skeletal muscle mass), SMI(skeletal muscle mass), and HOMA-IR (homeostasis model for insulin resistance) were calculated. Women assigned to the vitamin D supplement consumed 1,200 IU of vitamin D orally per week for 12 weeks. Women assigned to the exercise intervention performed a circuit training at an intensity of 60%~80% of HRmax with a frequency of 3 days per week for 12 weeks. Compared to control group, all groups had significant loss of body weight and increases in serum 25(OH)D after the 12-week intervention. ASM and SMI increased significantly in only vitamin D+exercise group. Regardless of treatments, no significant group differences were found in changed scores of fasting glucose, insulin, and HOMA-IR. In conclusion, vitamin D + exercise would improve the loss of ASM and SMI compared with vitamin D or exercise alone.
PURPOSE This study aimed to investigate the effects of continuous exercise and the accumulation of short-duration exercise for 12 weeks on body composition, physical fitness, and lifestyle disease indices in overweight men in their 30s. METHODS Participants in the continuous exercise group (CE; n=13) performed a circuit exercise program of 30 min/session, 3 sessions/week for 12 weeks. Participants in the accumulation of short duration exercise group (ASE; n=12) performed the same exercise time of 30 min per day, divided into three sessions of 10 min. Body composition, physical fitness, and lifestyle disease indices were measured pre- and post-test and were compared by utilizing a repeated two-way ANOVA. RESULTS 1) Regarding body composition, body weight, body mass index, skeletal muscle mass, waist circumference, and fat mass decreased significantly, while hip circumference increased significantly in the CE group. Waist circumference and skeletal muscle mass decreased significantly, while hip circumference increased significantly in the ASE group. 2) Regarding physical fitness, right grip strength, sit and reach, sit up, and maximal oxygen uptake increased significantly in both groups. 3) Regarding hypertension indices, there were no significant differences in both groups, but they showed a tendency to improve. 4) Regarding hyperlipidemia indices, triglycerides (TG) decreased significantly in both groups, and total cholesterol (TC) decreased significantly in the CE group. 5) Regarding diabetes indices, there were no significant differences in both groups, but a tendency to improve was noticed. 6) Regarding arteriosclerosis indices: TG/high density lipoprotein-cholesterol ratio decreased significantly in both groups, and the TC/high density lipoprotein-cholesterol ratio decreased significantly in the CE group. CONCLUSIONS We concluded that both the accumulation of short duration exercise and continuous exercise can be effective in improving body composition, physical fitness, and lifestyle disease in overweight men.
Purpose The study was designed to compare physical fitness, indices of lifestyle disease, and biochemical property of muscle according to sarcopenia and obesity in elderly women. Methods One hundred elderly women were alloted to one of four groups, i.e., sarcopenia+obesity (SO: n=20) group, sarcopenia (S: n=20) group, obesity (O: n=29) group, and normal (N: n=31) group. Criterion for sarcopenia was 'appendicular skeletal muscle mass (ASM)/height2<5.4 kg/㎡', and criterion for obesity was 'percent body fat>35%'. Dependent variables regarding physical fitness, lifestyle disease, and biochemical property of muscle were measured and compared among four groups. Results 1) Regarding daily living fitness, grip strength, upper arm flexion, sit-and-reach, up and go, and VO2max in SO group and S group were significantly lower than N group. Regarding isokinetic function, peak torque and average power in SO group and S group were significantly lower, and relative values to body weight in SO group and O group were significantly lower than N group. 2) Regarding hypertension, resting HR and RPP in SO group and O group were significantly higher than S group and N group. Regarding diabetes mellitus, fasting plasma glucose and HOMA-IR in SO group and O group were significantly higher than S group and N group. Regarding hyperlipidemia, HDL-C in SO group and O group were significantly lower than S group and N group. Regarding atherosclerosis, TC/HDL-C ratio and LDL-C/HDL-C ratio in SO group and O group were significantly higher than S group and N group. 3) Regarding biochemical property of muscle, IL-6 in SO group and O group were significantly higher than S group and N group. Conclusion It was concluded that physical fitness was declined in sarcopenia elderly, and that relative value of isokinetic function, indices of lifestyle disease, and inflammation markers were deteriorated in obesity elderly. Especially, the decline and deterioration of physical fitness and indices of lifestyle disease were even more severe in the elderly who had the both status. Therefore, the efforts should be made to prevent and improve sarcopenia and/or obesity.
Purpose Evaluating the aging of senior and providing optimal sevices are important things for successful aging. This study identified functional fitness related with heath of aged 65 years or older and developed an age scale (longevity fitness age) for assessing their aging. Methods Participants were 458 older people (166 male, 292 female). They were divided into healthy group and disease group. Healthy group was used for the development of the longevity age equation and disease group was for investigating the validity of the equation. Participants completed 13 function fitness variables. The first principal component obtained from a principal component analysis was used to compute the equation. All variables except for grip strength and carrying beans were correlated with chronological aged. Grip strength and variables related lower functional fitness had differences between healthy group and disease group. Finally, 4 variables were selected for the equation. Results It was the following: longevity fitness age=0.942*X1+2, 185*X2+0.673*X3+0.051*X4+0.588*chronological age+58.401, where X1=standing up from a supine position, sec (s), X2=maximum walking (s), X3=standing up and sitting down a chair (s), X4=one leg balance with eyes open (s). The longevity fitness age of healthy group do not have a difference compared to their chronological age but disease group had a difference significantly. Age difference (chronological age-longevity fitness age) of sedentary group in disease group was significantly bigger than its active group. Longevity fitness age could assess an aging of senior. Conclusion We suggest that it can use as the tool for early detecting senior who need the health care service.
This study was designed to compare physical fitness, blood lipids, and insulin resistance according to body mass index (BMI) and percent body fat (%BF) in 20s females. Sixty women, aged 20-29 yrs, volunteered to participate in the study as subjects. There were three groups, i.e., normal group (BMI < 24 kg·m-2 and %BF < 25%; n = 25), normal weight obese group (BMI < 24 kg·m-2 and 28% < %BF < 40%; n = 22), and obese group (BMI > 26 kg·m-2 and 30% < %BF < 40%; n = 13). Physical fitness, blood lipid profiles, and surrogate indices of insulin resistance were measured and compared among three groups. Main results of the present study were as follows: 1) There were significant differences in all variables regarding body composition among three groups. All values were lowest in normal group and highest in obese group. 2) There was significant difference in sit-and-reach among three groups, whereas no significant differences were found in other variables regarding physical fitness among three groups. 3) There were significant differences in all variables regarding blood lipids among three groups. In particular, total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), TC/HDL-C ratio, and LDL-C/HDL-C ratio were significantly higher in normal weight obese group than normal group. 4) There were significant differences in all variables regarding insulin resistance among three groups. Fasting plasma glucose and HOMA-IR were lowest in normal group and highest in obese group. It was concluded that there would be abnormal blood lipid profiles and insulin resistance in even normal weight obese individuals as well as general obese individuals in 20s females.
