Purpose The purpose of the study was to determine difference of body composition, bone mineral density and health-related fitness by physical activity level in young women. Methods A total of 90 women aged 19-29 years participated in this study. The subjects were divided into three groups (low, middle, and high level) according to the physical activity level estimated by bone-specific physical activity questionnaire(BPAQ). Body height and weight were measured. Body composition parameters including four sites of bone mineral density(BMD) were estimated by DXA (Hologic, QDR-4500, USA). Health-related fitness tests was assessed using sit & reach, grip strength, sit-ups, and VO2max. Statistical analysis was performed using SAS version 9.4. All data were presented in terms of means and standard deviations. One-way ANOVA was applied to determine difference of dependent variables by physical activity level. Duncan's multiple range test was used as a post-hoc test. The statistical significance level was set at p < .05. Results There were significant differences on body weight(F = 4.867, p = .01), body mass index(F = 5.053, p = .008) and fat-free mass(F = 8.364, p = .0001) among the three groups. Significant differences were found on whole body BMD(F = 16.730, p = .0001), lumbar BMD(F = 11.480, p = .0001), femur BMD(F = 42.182, p = .0001) and forearm BMD(F = 5.560, p = .005) among the three groups. There were also significant differences on sit and reach(F = 11.433, p = .0001), sit-ups(F = 17.972, p = .0001), VO2max(F = 3.106, p = .05) and duration of GXT(F = 7.479, p = .001). Conclusions There were differences on body composition, bone mineral density and health-related physical fitness by physical activity levels. Nevertheless, the questionnaire used in this study was not able to judge participation in various exercise types including aerobic exercise or resistance exercise. Therefore, in the future study, longitudinal study considering various types of physical activity and dietary intake will be needed.
The purpose of the study was to determine relationship of abdominal fat, adipocytokine, bone mineral density, and bone turnover markers in obese male adolescents. Twenty four male adolescents (obese: 12, normal: 12) volunteered to participate in the study. Anthropometry and skeletal maturity were measured. Body composition and bone mineral density were estimated by DXA (Hologic, QDR-4500, USA). Abdominal fat with total adipose tissue (TAT), visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), and visceral adipose tissue to subcutaneous adipose tissue ratio (VSR) were estimated by computed tomography (ECLOS, HITACH, Japan). Blood samples were obtained for and analysis of adipocytokines including leptin and adiponectin. Bone turnover markers, osteocalcin (OC), bone-specific alkaline phosphatase (BALP) for bone formation markers and N-terminal telopeptide (NTx), C-terminal telopeptide (CTx) for bone resorption markers were analysed. All data were analyzed utilizing SAS 9.3 (SAS Institute, NC, USA). Independent t-test was used to evaluate the differences between obese adolescents and normal adolescents. Pearson correlation analysis was applied to figure out the relationship between abdominal fat, adipocytokines, bone mineral density, and bone turnover markers. Multiple regression analysis was used to find out the factors of abdominal fat which influence on bone mineral density. A level of significance was set at p<.05. The results of the study indicated that fat tissue (p<.001), percent body fat (p<0.001), TAT (p<.001), VAT (p<.001), and SAT (p<0.001) were significantly higher in obese adolescents than normal adolescents. However bone mineral contents were significantly higher in normal adolescents. Normal adolescents have significantly higher whole body BMD and lumber BMD than obese adolescents. Abdominal fat including VAT and SAT related negatively with whole body BMD and lumbar BMD. Leptin related negatively with BMD whereas adiponectin related positively with BMD. NTx for bone resorption marker related positively with abdominal fat. Visceral adipose tissue was a predictor for whole body BMD and lumbar BMD in explaining 46% and 32% in adolescents. In conclusion, obese male adolescents have lower whole body BMD and lumbar BMD than normal adolescents. Abdominal fat including VAT and SAT related negatively with whole body BMD and Lumbar BMD. And leptin and adiponectin were closely related with BMD. Finally, visceral adipose tissue was a predictor for whole body and lumbar BMD in adolescents.
Purpose Osteoporosis is a systemic metabolic bone disease characterized by gradual decrease of bone mass and damage of the bone microstructure. In particular, postmenopausal osteoporosis is the most common type in women after menopause. This study aims to investigate the effects of combined exercise training on bone mineral density (BMD) and OPG/RANKL mRNA levels in ovariectomized rats. Methods A total of 40 Sprague-Dawley female rats were randomly divided into four groups: (1) CON (sham-operation, n=10), (2) OVX (ovariectomy, n=10), (3) OVX-REX (ovariectomy-resistance exercise, n=10), and (4) OVX-ARE (ovariectomy-combined aerobic and resistance exercise, n=10). Combined exercise training was performed on a treadmill and ladder adapted to rats in alternate days (4 days/wk, for 12 wk). Results Compared to the OVX group, all exercise treatments increased BMD and bone breaking force(p<0.05). In the bone turnover markers, serum C-terminal telopeptides of type-1 collagen (CTX-1) was significantly decreased in the exercise groups compared with OVX group and osteocalcin (OC) level was increased in the exercise groups (p<0.05). Additionally, in the exercise groups, expression of OPG mRNA was significantly increased compared with OVX group (p<0.05), and RANKL mRNA was slightly decreased but no significant between groups. Furthermore, OVX-ARE group showed more effects than OVX-REX group. Conclusions These results suggest that combined exercise may be a more effective therapeutic strategy to prevent and delay postmenopausal osteoporosis than resistance-only training.
Purpose The purpose of this study was to investigate the effects of low-intensity resistance training with blood flow restriction on serum VEGF, bone markers and bone mineral density in elderly women. Methods The subjects were divided into three groups: low-intensity resistance training with blood flow restriction(BFR-LRT, n=8); high intensity resistance training(HRT, n=8); low- intensity resistance training (LRT, n=5). Both the BFR-LRT and LRT groups worked out knee extension and leg curl exercises at 20% of each estimated one-repetition maximum(1RM) and HRT group worked out knee extension and leg curl exercises at 70% of each estimated 1RM 3 days per week for 12 weeks. Results As a result after 12 weeks, serum VEGF level have increased significantly among BFR-LRT group compared to HRT and LRT groups. Serum Bone ALP level have increased significantly among BFR-LRT and HRT groups compared to LRT group. Calcaneus BMD have increased significantly among BFR-LRT and HRT groups compared to LRT group. Conclusions In conclusion, despite using low-intensity load, BFR-LRT is a efficient training alternative to HRT for improving bone metabolism in older women.
The purpose of this study was to investigate the relationship between depression and bone mineral density in Korean elder men (55+), and test mediating role of health behaviors. Korean National Health and Nutrition Examination Survey 2006-2011 data were analyzed. Bone mineral density was measured using DXA. Depression was measured by whether a participant had diagnosed depression, depressed mood lasted longer than 2 weeks, and/or suicidal thinking. Mediating health behaviors were serum vitamine D, calcium intake, high-risk drinking, endurance physical actiity, and resistance exercise. The associations among depression, health behaviors, and bone mineral density with demographic covariates were tested by linear regression, logistic regression, and path analysis. Diagnosed depression was not significantly associated with bone mineral density. Men who experienced substantial depressed mood and suicidal thinking has significantly lower bone mineral density than non-experienced counterparts. The effect of suicidal thinking on bone mineral density was mediated by endurance physical activity only. This study results suggest that elder men who experienced severely depressed mood and suicidal thinking were at-risk population for osteopenia. Also, physical activity intervention seems to be a priority to prevent osteoporosis comorbidity in depressed people.
The aim of the study was to examine the tracking of body composition and physical fitness in boys and girls for 6 years. Thirty-seven boys and girls participated throughout the study. All measurements were performed annually. Body height, body weight, circumferences and skinfold thicknesses were measured and skeletal maturity was assessed. Body composition and bone mineral density were measured by DXA. Nine physical fitness tests were administered. Results of the study showed that there are significant interaction effects of time and group for body height(p<.01), waist circumference(p<.001), and skinfolds at triceps(p<.01), suprailiac(p<.01), thigh(p<.001) and medial calf(p<.01). All anthorpometric variables except skinfold thickness increased during the study period. Significant interaction effects of time and group were found for percent body fat(p<.05) and bone mineral density(p<.01). Percent body fat and fat tissue increased in boys from 7 to 11 years, then decreased in 12 years. Lean tissue(p<.001), bone mineral content(p<.001) and bone mineral density(p<.001) increased both in boys and girls throughout the study. There were significant interaction effect of time and group on sit and reach, standing long jump and sit-ups. In conclusion, percent body fat and fat tissue increased until 11 years, lean tissue and bone mineral density increased throughout the study both in boys and girls.
PURPOSE This study investigated the associations between physical fitness and fall efficacy with thigh circumference in elderly women with osteopenia/osteoporosis. METHODS A total of 166 female participants aged 76.3±5.0 years with –1.0≥T-score of femur neck bone mineral density were voluntarily recruited from local community centers. The participants were classified as low 25%, middle 50%, and high 25% groups based on their thigh circumference. Physical fitness measurements, including strength, flexibility, aerobic endurance, and balance were measured with a standardized protocol. The Korean version of the fall efficacy scale (K-FES) was used to assess fall efficacy. Logistic regression analysis was used to estimate odd ratio (OR) of poor physical fitness and low fall efficacy according to thigh circumference levels. RESULTS In terms of physical fitness, the middle 50% group (OR=0.430, 95% CI=0.194-0.953) and high 25% group (OR=0.129, 95% CI=0.049-0.343) had significantly higher linear trend for poor physical fitness compared to the low 25% group (reference), (p<0.001). In fall efficacy, the middle 50% group (OR=0.279, 95% CI=0.119-0.656) and high 25% group (OR=0.100, 95% CI=0.036-0.275) had significantly higher linear trend for low fall efficacy compared to the low 25% group (reference) (p<0.001). CONCLUSIONS The current findings suggest that maintaining high thigh circumference via regular physical activity and diet may contribute to attenuation of decreased risk for poor physical fitness and low fall efficacy in elderly women with osteopenia/osteoporosis.
Purpose The purpose of this study were to assess physiological and biochemical characteristics in elderly women with osteosarcopenic obesity (OSO), and to analyze relationships among irisin, adipokines and bone metabolism markers. Methods 126 elderly women were selected and among them 10 women were classified into OSO group (76.9±5.2 yrs) and 14 women were classified as a NOSO group (72.9±5.6 yrs). Physique, body composition and bone mineral density were measured. Senior fitness tests were 30-s chair stand, 30-s arm curl, chair sit-and-reach, back scratch, 8-foot up-and-go, grip strength, and 2-min step test. Isokinetic muscle strength was measured by isokinetic dynamometer (Cybex 770, USA). Nutrition intake and physical activity were administered. Biochemical parameters including irisin, FNDC-5, leptin, adiponectin, CTx, 25(OH)D, osteocalcin, and PTH were measured. All data were analyzed by SAS 9.4. Independent t-test was applied to compare between OSO and NOSO groups. Multiple regression analysis was used. The level of significance was set at .05. Results The results of the study showed that there were significantly high for waist circumference, hip circumference, WHR, and BMI in OSO group compared to those of NOSO group. Higher results were also obtained for fat tissue and percent body fat but significantly low for lumbar bone mineral density. OSO group showed significant lower results for grip strength and 2-min step test compared to NOSO group. Peak torque, and relative peak torque at 60° were significantly lower for left and right knee flexion in OSO group. Protein intake was significantly low in OSO group, but no difference was obtained in level of physical activity between two groups. Irisin was significantly related to adiponectin, FNDC-5 and osteocalcin in explaining 35.2%, 81.5% and 92.1% of the variance, respectively. Conclusions This study shows that elderly women with OSO have higher results for physique and body composition parameters except body height. However, lower values were obtained for functional fitness, and isokinetic muscle strength. OSO may have more risks for metabolic syndrome, bone fractures, fall, lack of daily physical activity and limit of locomotion due to the imbalance of quadriceps and biceps femoris in non dominant leg. This study suggests that criteria and mechanism of OSO should be clarified by follow-up study.
[Purpose] The purpose of this study was to provide the physiological characteristics of female adults in their 30s by comparing the body composition and the maximal strength of the knee extension and flexion and bilateral ratio and ipsilateral ratio(H/Q: Hamstring and Quadriceps ratio) depending on age. [Methods] Body composition was measured by Hv-ps 7681(GE medical systems Lunar, USA). Isokinetic lower limb muscular strength was measured by Isomed2000(D&R Ferstl GMBH, Germany). 92 volunteers who were chosen by our selection criteria agreed to participate in our study. The participants were divided into three groups depending on age and classified as female adults in twenties(n=30), in thirties(n=34), in forties(n=28). To evaluate differences according to age, One-way ANOVA was used. [Results] The result in the test for female adults is as follows. In body composition, there were significant differences in lean mass, bone mineral density in the legs area among groups(p<.05). In isokinetic test, there were significant differences in muscular strength among groups in extensor of knee(p<.05). [Conclusion] The finding revealed that strength training based on the characteristics depending on age is required and ipsilateral ratio needs to be improved.
